Surfactant and pharmaceutical compositions thereof

专利名称：Surfactant and pharmaceutical compositions

thereof for use in the treatment ofrespiratory distress syndrome

发明人：Tsunetomo, Takei,Yosaku, Kanazawa,Kazuo,

Masuda,Yuji, Tanaka

申请号：EP84301513申请日：19840307公开号：EP0119056A3公开日：19860625

摘要：A surfactant having the capacity of reducing the surface tension in pulmonaryalveoli significantly is provided. The surfactant consists essentially of, based on the totalweight of the surfactant, 50.6-85.0% of choline phosphoglyceride, 4.5-37.6% of an acidphospholipid, 4.6-24.6% of a fatty acid or its analogue and 0.1-10.0% of a lipoproteinderived from the lung of a mammal. These components co-operate to form a kind of filmat a gas-liquid interface within pulmonary alveoli and reduce the surface tension. Apharmaceutical composition comprising the surfactant is useable for the clinicaltreatment of respiratory distress syndrome.

申请人：TOKYO TANABE COMPANY LIMITED

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