专利名称:Topical composition for follicular delivery of
an ornithine decarboxylase inhibitor
发明人:Joyce T. Chou,Prakash Parab申请号:US10219087申请日:20020813公开号:US07374770B2公开日:20080520
专利附图:
摘要:Polyethylene glycol ethers of alkyl alcohols having the general formulaCH(CH)CH(OCHCH)OH wherein x is 8 to 20 (of which ceteareth-20, steareth-20 andsteareth-100 are preferred), poloxamer 185, poloxamer 407, N,N-dimethyl dodecylamine
N-oxide, and mixtures thereof, are employed to increase follicular delivery and/orfollicular residence time of certain water soluble ornithine decarboxylase inhibitors ofwhich 2(difluoromethyl)-2,5-diamino pentanoic acid and its pharmaceutically acceptablesalts, hydrates, optical enantiomers and racemic mixture are preferred.
申请人:Joyce T. Chou,Prakash Parab
地址:Fremont CA US,Monroe Township NJ US
国籍:US,US
代理机构:Wilson Sonsini Goodrich & Rosati
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