专利名称:STABILIZED SYNTHETIC IMMUNOGEN
DELIVERY SYSTEM
发明人:SOKOLL, KENNETH, K.申请号:US0304711申请日:20030214公开号:WO03068169A3公开日:20070315
摘要:The present invention provides an immunostimulatory complex specificallyadapted to act as adjuvant and as a peptide immunogen stabilizer. The
immunostimulatory complex comprises a CpG oligonucleotide and a biologically activepeptide immunogen. The immunostimulatory complex is particulate and can efficientlypresent peptide immunogens to the cells of the immune system to produce an immuneresponse. The immunostimulatory complex may be formulated as a suspension forparenteral administration. The immunostimulatory complex may also be formulated inthe form of w/o-emulsions, as a suspension in combination with a mineral salt suspensionor with an in-situ gelling polymer for the efficient delivery of an immunogen to the cellsof the immune system of a subject following parenteral administration, to produce animmune response which may also be a protective immune response.
申请人:UNITED BIOMEDICAL INC.
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