专利名称：CVS TRANSPLANTATION FOR TREATMENT
OF BACTERIAL VAGINOSIS
发明人：Laura Ensign,Richard Cone,Justin Hanes申请号：US15174540申请日：20160606
公开号：US20160279182A1公开日：20160929
摘要：Methods and materials for treating bacterial vaginosis (“BV”) are provided.Cervicovaginal secretions (“CVS”) from a woman with vaginal microbiota dominated(>50%) by one of the species of typically found in the human vagina, e.g. , is transplantedto women with BV as a method for restoring beneficial vaginal microbial communitiesand/or increasing resistance to sexually transmitted disease. Efficacy can be enhanced, orthe properties of the endogenous CVS improved, through administration of an acidifyingagent such as lactic acid. The examples demonstrate the role of healthy CVS in diseaseresistance, and the effect of pH on CVS properties. The examples also describe thecollection and transplantation of healthy beneficial CVS into women at risk for, or aftertreatment for, BV.
申请人：The Johns Hopkins University
地址：Baltimore MD US
国籍：US
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