Intubation devices with local anesthetic effect fo

专利名称：Intubation devices with local anesthetic

effect for medical use

发明人：Richard R. Jackson申请号：US07/527593申请日：19900523公开号：US05279594A公开日：19940118

摘要：A compound with topical anesthetic properties is incorporated in polymericmaterial making up the wall of a tube of intubation devices for introduction into bodypassages of an animal. A hydrophobic anesthetic compound is used which is more solublein the polymeric wall material of the tube than in water. Because of the hydrophobicproperties of the anesthetic compound, a quantity of anesthetic compound can be storedin solution in the polymeric wall material of the tube and this stored anesthetic

compound is not washed out by the aqueous fluid which is present in the body passage.As a result, the anesthetic compound is transferred only to the contiguous tissue of thebody passage and not disseminated systemically through the aqueous fluids. When thetube is in place within a body passage the anesthetic compound diffuses to the surface ofbody tissue touched by the tube where its anesthetic effect suppresses discomfort andundesired rejection reactions. Since the anesthetic compound is thus dispensed only tothe contiguous tissue of the body passage, the quantity of anesthetic compound storedin the tube wall is sufficient to maintain effective anesthesia of the body passage forhours or days, and undesired effects of a general dissemination through the body areavoided.

申请人：JACKSON; RICHARD R.

代理机构：Fish & Richardson

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