专利名称：Microorganisms and processes for enhanced
production of pantothenate
发明人：R Rogers Yocum,Thomas A Patterson,Janice
G Pero,Theron Hermann
申请号：US10520210申请日：20020703
公开号：US20060099692A1公开日：20060511
摘要：The present invention features improved methods for the enhanced productionof pantoate and pantothenate utilizing microorganisms having modified pantothenatebiosynthetic enzyme activities and having modified methylenetetrahydrofolate (MTF)biosynthetic enzyme activities. In particular, the invention features methods for enhancingproduction of desired products by increasing levels of a key intermediate, ketopantoate,by increasing enzymes or substrates that contribute directly or indirectly to its synthesis.Recombinant microorganisms and conditions for culturing same are also featured. Alsofeatured are compositions produced by such microorganisms.
申请人：R Rogers Yocum,Thomas A Patterson,Janice G Pero,Theron Hermann
地址：Lexington MA US,North Attleboro MA US,Lexington MA US,Kinnelon NJ US
国籍：US,US,US,US
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