专利名称:Antisense modulation of focal adhesion
kinase expression
发明人:Brett P. Monia,William A. Gaarde,Pamela S.
Nero
申请号:US10646569申请日:20030822
公开号:US20040192628A1公开日:20040930
摘要:Compounds, compositions and methods are provided for inhibiting FAK
mediated signaling. The compositions comprise antisense compounds targeted to nucleicacids encoding FAK. Methods of using these antisense compounds for inhibition of FAKexpression and for treatment of diseases, particularly cancers, associated withoverexpression or constitutive activation of FAK are provided.
申请人:MONIA BRETT P.,GAARDE WILLIAM A.,NERO PAMELA S.
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