专利名称：Therapeutic agents and methods of use
thereof for the modulation of angiogenesis
发明人：Gary L. Olson,Christopher Self,Lily
Lee,Charles Michael Cook,Jens Birktoft,BarryMorgan,Christopher C. Arico-Muendel
申请号：US10001945申请日：20011101公开号：US07084108B2公开日：20060801
专利附图：
摘要：The present invention provides angiogenesis inhibitor compounds comprising a
MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositionscomprising the angiogenesis inhibitor compounds and a pharmaceutically acceptablecarrier. The present invention also provides methods of treating an angiogenic disease,e.g., cancer, in a subject by administering to the subject a therapeutically effective amountof one or more of the angiogenesis inhibitor compounds of the invention.
申请人：Gary L. Olson,Christopher Self,Lily Lee,Charles Michael Cook,JensBirktoft,Barry Morgan,Christopher C. Arico-Muendel
地址：Mountainside NJ US,West Caldwell NJ US,Edison NJ US,Mendham NJ US,NewYork NY US,Franklin MA US,West Roxbury MA US
国籍：US,US,US,US,US,US,US
代理机构：Lahive & Cockfield, LLP
代理人：Giulio A. DeConti, Jr.,Maria Laccotripe Zacharakis
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