专利名称：ATTENUATED BACTERIA USEFUL IN
VACCINES
发明人：ARTHUR KEITH TURNER,JUDITH
GREENWOOD,JONATHAN CLIVE
STEPHENS,JULIET CLAIRE BEAVIS,MICHAELJAMES DARSLEY
申请号：US13073999申请日：20110328
公开号：US20110189225A1公开日：20110804
摘要：The invention provides strains of bacteria, especially enterotoxigenic ,attenuated by mutations in the genes encoding enterotoxins (LT, ST, EAST1) andoptionally further attenuated by deletion of additional chromosomal genes. In additionthe invention provides strains of attenuated bacteria expressing immunogenic but non-toxic variants of one or more of these enterotoxins. These bacteria are useful as a vaccineagainst diarrhoeal disease.
申请人：ARTHUR KEITH TURNER,JUDITH GREENWOOD,JONATHAN CLIVESTEPHENS,JULIET CLAIRE BEAVIS,MICHAEL JAMES DARSLEY
地址：Cambridge GB,Cambridge GB,Cambridge GB,Cambridge GB,Cambridge GB
国籍：GB,GB,GB,GB,GB
更多信息请下载全文后查看
因篇幅问题不能全部显示，请点此查看更多更全内容