专利名称：Expression system
发明人：Ethel Diane Williamson,Leslie William James
Baillie,Julie Miller
申请号：US10483150申请日：20040625
公开号：US20040235140A1公开日：20041125
摘要：A recombinant microorganism comprises an asporogenic strain in which a geneencoding a protease enzyme has been downregulated or inactivated. In particular sigmafactorspoIIAC is inactivated such that the strain is asporogenic. These strains areparticularly useful as expression vehicles for proteins such as protective antigen (PA) of
申请人：WILLIAMSON ETHEL DIANE,BAILLIE LESLIE WILLIAM JAMES,MILLER JULIE
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