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Process for the preparation of 1,2-benzisothiazoli

2020-04-25 来源:易榕旅网
专利内容由知识产权出版社提供

专利名称:Process for the preparation of 1,2-benzisothiazolin-3-ones

发明人:Mark Robert James申请号:US08/875075申请日:19970717公开号:US05936094A公开日:19990810

摘要:A process for making a 2-alkylbenzisothiazolinone which comprises reacting abisamide of formula ##STR1## in water or an organic liquid containing water with abisulphite or bisulphite release agent to form a Bunte salt and converting the Bunte saltunder alkaline conditions to 2- alkyl-BIT. R is alkyl. Preferred substituents R are butyl,hexyl, 2- ethylbutyl and 2-ethylhexyl.

申请人:ZENECA LIMITED

代理机构:Pillsbury Madison & Sutro LLP

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